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Using two separate drugs to lose weight can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight loss and the people who go through it you need to err on the side of caution and permit the FDA do its job and demand some investigation be done so your public knows the side effects and risks of the medications before we drive them. Keep in mind that drug companies have been in business to generate money and that they would say everything to keep people on his or her medications. Researchers discovered that participants using this drug for a year, dropped a few pounds within one month and have kept the load off throughout the 56 weeks in the study. Contrave is really a combination with the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs that are made up of more than one active ingredient, which can make them more effective and safer. Combo-pilling is the newest fad or even better the newest ahead under scrutiny and thus it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular will be the fact that at the time of right now there aren't long term prescription slimming capsules that have been authorized by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations happen to be rejected or have yet to be approved by the FDA. Seizures are a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug can also raise blood pressure levels and heart rate, and mustn't be used in people with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure and heartrate and must not be used in patients with uncontrolled high blood pressure level, as well as by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients having a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients towards the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stop smoking. New UCLA study on smokers with mental, drug, and alcohol problems