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The U.S. Food and Drug Administration reviewed Contrave on December 7, and approved the drug 13-7, stating the advantages of the drug outweighs potential risk of a possible increase in blood pressure. Using two separate drugs to lose weight can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the those who go through it you need to err assisting caution and allow the FDA do its job and demand some study be done so your public knows the side effects and hazards of the medications before we take them. Keep in mind that drug companies will be in business to make money and that they would say anything to keep people on their medications. Researchers discovered that participants taking this drug to get a year, lost excess weight within one month and have kept the load off through the entire 56 weeks from the study. Contrave is a combination from the drugs naltrexone and bupropion, which appears to reflect a brand new trend of weight-loss drugs which might be made up of several active ingredient, which might make them more potent and safer. Combo-pilling may be the newest fad or in addition to this the newest into the future under scrutiny and thus it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular could be the fact that by right now there are no long term prescription weight loss supplements that have been approved by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be authorized by the FDA. Seizures are a side effect with Contrave and shouldn't be taken in people who have seizure disorders. The drug could also raise blood pressure level and heartrate, and must not be used in people with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise hypertension and heartbeat and must not be used in patients with uncontrolled high hypertension, and also by you are not heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients with a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients to the increased chance of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stop smoking. 
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